S.G. Ayre, M.D., D. P. Garcia Bellon, M.D., D. P. Garcia, Jr., M.D. Medical hypotheses 55.4 (2000): 330-334. Summary The endogenous molecular biology of cancer cells involves autocrine and paracrine secretion of insulin and insulin-like growth-factors I and II, which subserve energy production and growth stimulation, respectively, in these cells. These activities confer on cancer its malignant potential, working …
Continue reading “Insulin, chemotherapy, and the mechanisms of malignancy: the design and the demise of cancer”
Steven G. Ayre MD traveled the world to present his findings on the work of the Drs. Donato Perez Garcia. In May 2001, he presented to a group of physicians attending a conference hosted by the American College for the Advancement of Medicine (ACAM) in Nashville TN. Audio excerpts with accompanying slides are below: Part …
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Steven G. Ayre MD The hormone insulin is recognized as having actions that affect the transmembrane transport of different substances, particularly glucose, into numerous different kinds of cells. Insulin is a large polypeptide molecule with a molecular weight of 5808. It consists of an A chain and a B chain, connected together by two disulfide …
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S.G. Ayre. Medical Hypotheses 29:283-291, 1989 Abstract The Human Immunodeficiency Virus (HIV) is the causative agent of AIDS and this has been found to be neurotropic. For this reason the development of an effective strategy for the delivery of antiviral drugs across the blood-brain barrier is of paramount importance in the treatment of HIV infection. …
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Steven G. Ayre, Donato Perez Garcia y Bellon and Donato Perez Garcia, Jr. — European Journal of Cancer 1990; 26(11-12):1262-3 We have developed a neoadjuvant chemohormonal therapy for breast carcinomas without surgery or radiotherapy. Cyclophosphamide, methotrexate, and 5-fluorouracil are administered, with insulin as a biological response modifier to potentiate anticancer drug effects [1]. This regimen …
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ABSTRACT Insulin may be used as a biological response modifier along with low-dose cyclophosphamide, methotrexate, and 5-fluorouracil (CMF) as neoadjuvant chemohormonal therapy for breast cancer. Insulin and insulin-like growth factor-1 (IGF-1) are autocrine and/or paracrine growth factors in human breast cancer cells (HBCC). We administer pharmacologic doses of insulin to manipulate these endogenous growth-promoting mechanisms, …
Continue reading “International Congress on Neo-Adjuvant Chemotherapy – Paris 1991”
The design and the demise of cancer – Steven G. Ayre MD I always thought a petard was some sort of medieval weapon – like one of those things with a big rounded blade and a smaller pointy thing sticking out of the other end, all mounted atop a longish wooden shaft. Spanish, I thought. Thus, …
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Publications and Essays on IPT Insulin Potentiation Therapy: A Renaissance in Cancer Chemotherapy - How Does it Work? S.G. Ayre, MD The Physiology and Clinical Pharmacology of Insulin in Relation to its Application in Insulin Potentiation Therapy - Steven G. Ayre MD Poster Presentation at the Third Annual Comprehensive Cancer Management Conference, Washington DC, June 2000 Hoist …
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Cancer is one condition for which the treatment is often considered worse than the disease. The rapid growth of alternative medicine in recent years has been driven by people’s desires for kinder and gentler treatments for this disease. Insulin Potentiation Therapy (IPT) fulfills this need. Because Insulin Potentiation Therapy improves the targeting of chemotherapy to …
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